Working towards risk stratification for ascending aortic dilatation in pediatric Turner syndrome patients: results of a longitudinal echocardiographical observation

Conclusions: Marked progression of aortic diameters leading to the development of dilatation can be observed in TS patients during childhood and stresses the importance of close surveillance during childhood. Main risk factors are BAV and complete monosomy 45X0. A beneficial influence of estrogen substitution can be suspected but needs further investigation.What is known:• Patients with Turner syndrome are at an increased risk for aortic dilatation and dissection.• The presence of BAV and complete monosomy 45X are additional risk factors.What is new:• Aortic dilatation can be detected in pediatric patients with Turner syndrome.• Relevant progression in childhood is possible in at-risk individuals and warrants close surveillance.
Source: European Journal of Pediatrics - Category: Pediatrics Source Type: research