A Young Woman With Hypertonia, Severe Scoliosis, and Encephalopathy

A 31-year-old woman was seen with contractures in her fingers and toes, carpal inversion, dysarthria, dysphagia, hypertonia, decreased tendon reflexes, absence of Babinski sign, and no psychiatric problems and significant global atrophy. What is your diagnosis?
Source: JAMA Neurology - Category: Neurology Source Type: research