Research on promoting the asymmetric reaction of phenylacetylene with aldehydes by chloramphenicol base ligands

Chirality. 2023 Nov 16. doi: 10.1002/chir.23631. Online ahead of print.ABSTRACTA series of chiral ligands were synthesized using chloramphenicol base as starting materials. These ligands were applied to the asymmetric catalytic reactions of terminal alkynes with aldehydes to obtain a propargyl alcohol product in high yield (80-94%) with excellent enantioselectivities (82-96%).PMID:37974359 | DOI:10.1002/chir.23631
Source: Chirality - Category: Molecular Biology Authors: Source Type: research