Age-dependent effects of the β < sub > 3 < /sub > adrenoceptor agonist CL316,243 on human and rat detrusor muscle strips

In conclusion, our findings suggest differential age-dependent changes in human β3 adrenoceptor-dependent attenuation of detrusor contraction in terms of electromechanical versus pharmacomechanical coupling; they may help understand the differential responsiveness of OAB patients to β3 agents.PMID:37993748 | DOI:10.1007/s00424-023-02877-x
Source: Pflugers Archiv : European Journal of Physiology - Category: Physiology Authors: Source Type: research