Incorporating variable RBE in IMPT optimization for ependymoma

CONCLUSION: We demonstrated the feasibility of directly incorporating variable RBE models in IMPT optimization. A hybrid RBE optimization strategy showed potential for clinical implementation by maintaining all current dose limits and reducing the incidence of high RBE in critical normal tissues in ependymoma patients.PMID:37985962 | DOI:10.1002/acm2.14207
Source: Journal of Applied Clinical Medical Physics - Category: Physics Authors: Source Type: research