Larger ischemic cores and poor collaterals among large vessel occlusions presenting in the late evening

Components critical to cerebral perfusion have been noted to oscillate over a 24-h cycle. We previously reported that ischemic core volume has a diurnal relationship with stroke onset time when examined as dichotomized epochs (i.e. Day, Evening, Night) in a cohort of over 1,500 large vessel occlusion (LVO) patients. In this follow-up analysis, our goal was to explore if there is a sinusoidal relationship between ischemic core, collateral status (as measured by HIR), and stroke onset time.

Source: Journal of Stroke and Cerebrovascular Diseases - October 4, 2023 Category: Neurology Authors: Anirudh Sreekrishnan, Steffen Tiedt, Pierre Seners, Nicole Yuen, Jean-Marc Olivot, Michael Mlynash, Maarten G. Lansberg, Jeremy J. Heit, Sarah Lee, Patrik Michel, Davide Strambo, Alexander Salerno, Jos é Bernardo Escribano Paredes, Emmanuel Carrera, Greg Source Type: research