Oseltamivir May or May Not Reduce Hospitalizations

To the Editor We read with great interest the work by Hanula and colleagues evaluating the association between oseltamivir and hospitalization. The authors performed a meta-analysis of 15 randomized clinical trials and concluded that “…oseltamivir was not associated with a reduced risk of hospitalization but was associated with increased gastrointestinal adverse events. To justify continued use for this purpose, an adequately powered trial in a suitably high-risk population is justified.” We consider a few caveats to be wo rth discussing.
Source: JAMA Internal Medicine - Category: Internal Medicine Source Type: research