GSE247770 RNAseq of VP882 phage activation in V. cholerae

Contributors : Marcel Sprenger ; Malte Siemers ; Kai PapenfortSeries Type : Expression profiling by high throughput sequencingOrganism : Vibrio choleraeMany, if not all, bacteria use quorum sensing (QS) to control gene expression and collective behaviours, and more recently QS has also been discovered in bacteriophages (phages). Phages can produce communication molecules of their own, or “listen in” on the host’s communication processes, in order to switch between lytic and lysogenic modes of infection. In this project, we studied the interaction of Vibrio cholerae, the causative agent of cholera disease, with the lysogenic vibriophage VP882. The lytic cycle of VP882 is induce d by the QS molecule DPO (3,5-dimethylpyrazin-2-ol), however, the global regulatory consequences of DPO-mediated VP882 activation have remained unclear.

Source: GEO: Gene Expression Omnibus - November 20, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Vibrio cholerae Source Type: research