A Challenging Case of Ectopic ACTH Syndrome with Bronchial Carcinoid and Literature Review

J Clin Res Pediatr Endocrinol. 2023 Nov 9. doi: 10.4274/jcrpe.galenos.2023.2023-7-6. Online ahead of print.ABSTRACTHere we report an adolescent boy diagnosed with ectopic ACTH (Adrenocorticotropin hormone) syndrome (EAS) caused by atypical bronchial carcinoid. The patient was evaluated multidisciplinaryly: he had surgery and took chemotherapy and radiotherapy treatments afterward. The patient is still under our follow-up. Until today eighteen pediatric and adolescent patients with EAS because of bronchial carcinoid tumors were reported in 13 case reports and literature reviews. Ectopic ACTH syndrome caused by bronchial carcinoids is very rare in children and adolescents. Careful diagnostic evaluation and rapid treatment should be started immediately. Although complete remission is possible in bronchial carcinoids, atypical carcinoids have a more aggressive nature. A multidisciplinary approach and follow-up will improve quality of life and survival.PMID:37942887 | DOI:10.4274/jcrpe.galenos.2023.2023-7-6

Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - November 9, 2023 Category: Endocrinology Authors: Sema Nilay Abseyi Zeynep Şıklar Elif Özsu Ayten Kay ı Cangır Emel Cabi Ünal Nurdan Ta çyıldız Zehra Aycan Merih Berbero ğlu Source Type: research