Bacteria manipulate host cells with channel-forming effectors

Trends Microbiol. 2023 Nov 10:S0966-842X(23)00302-5. doi: 10.1016/j.tim.2023.10.013. Online ahead of print.ABSTRACTBacterial pathogens deliver effectors into host cells mostly to manipulate signaling and metabolic molecules, thereby subverting host immunity. A recent study by Nomura et al. demonstrates that certain effectors create membrane channels in host cells, enabling bacteria to access water and solutes for multiplication.PMID:37953153 | DOI:10.1016/j.tim.2023.10.013

Source: Trends in Microbiology - November 12, 2023 Category: Microbiology Authors: Yukun Liu Shuguo Hou Source Type: research