Pitfalls in anticoagulant-related nephropathy

Clin Nephrol. 2023 Oct 25. doi: 10.5414/CN111156. Online ahead of print.ABSTRACTAnticoagulant-related nephropathy (ARN) is a rare but important disease and often misdiagnosed. The hallmark of the diagnosis is acute kidney injury (AKI) superimposed on preexisting kidney disease due to anticoagulation-induced glomerular hemorrhage with histologic features of widespread tubular obstruction by red blood cells and red cell casts. As ARN is a diagnosis of exclusion only proven by renal biopsy, the diagnosis is often unlikely to be confirmed histologically because of fear of biopsy-related bleeding during anticoagulant therapy. Given the large differential diagnosis in AKI, diagnosing ARN remains a challenge for clinicians. A case report and the pitfalls related to diagnosis and management will be discussed in this paper.PMID:37877298 | DOI:10.5414/CN111156

Source: Clinical Nephrology - October 25, 2023 Category: Urology & Nephrology Authors: Romeo V Kock Kenrick Berend Sandrine Florquin Hugo Ten Cate Source Type: research