Atrial fibrillation phenotypes: the route to personalised care?

Atrial fibrillation (AF) is the most common arrhythmia in adults and is responsible for significant morbidity and mortality. Recent data support the move towards personalisation of care in AF, which is of particular importance given the multiple, complex, management decisions that need to be made. Paradigms in AF care have also changed significantly recently due to the results of EAST-AFNET 41 that demonstrated the benefits of rhythm control for the reduction in adverse cardiovascular outcomes. Catheter ablation is used increasingly in AF for the improvement of symptoms and potentially the reduction of adverse events in certain populations. However, there is a currently a ceiling to the success rates of catheter ablation in AF. Several additional lesion sets beyond pulmonary vein isolation have been advocated; however, none have been reliably shown to be beneficial in unselected patients.2 Tailoring of treatments based on AF phenotype may therefore...
Source: Heart - Category: Cardiology Authors: Tags: Editorials Source Type: research