Pathogenicity of functionally activated PD-1 < sup > + < /sup > CD8 < sup > + < /sup > cells and counterattacks by muscular PD-L1 through IFN γ in myositis

In conclusion, PD-1+CD8+ T cells rather than PD-1-CD8+ T cells were a pathogenic subset of IIMs. Muscular PD-L1 was regulated by IFNγ and exerted protective properties in IIMs.PMID:37931332 | DOI:10.1016/j.jaut.2023.103131
Source: Journal of Autoimmunity - Category: Allergy & Immunology Authors: Source Type: research