LC –MS Approach to Decipher a Light Chain Chromatographic Peak Splitting of a Monoclonal Antibody

ConclusionLiquid chromatography-mass spectrometry (LC –MS) has been utilized extensively to assess PQAs of biological therapeutics. In this study, a generalizable LC–MS-based approach was developed to enable identification and quantitation of the isoAsp-containing peptides.
Source: Pharmaceutical Research - Category: Drugs & Pharmacology Source Type: research