Benefit of postoperative regional nodal irradiation in patients receiving preoperative systemic therapy with docetaxel/carboplatin/trastuzumab/pertuzumab for HER2-positive breast cancer

CONCLUSION: With a rare incidence of LRR, RNI did not significantly affect LRR or DFS in patients with HER2-positive breast cancer after with PST-TCHP. However, intensive systemic treatment is required for advanced diseases (C/D). Selective de-intensified RNI and intensified systemic treatment should be investigated in future studies.PMID:37924622 | DOI:10.1016/j.breast.2023.103594

Source: Breast - November 4, 2023 Category: Cancer & Oncology Authors: Nalee Kim Ji-Yeon Kim Won Park Won Kyung Cho Tae Gyu Kim Young-Hyuck Im Jin Seok Ahn Jeong Eon Lee Seok Jin Nam Seok Won Kim Jonghan Yu Byung Joo Chae Sei Kyung Lee Jai-Min Ryu Yeon Hee Park Haeyoung Kim Source Type: research