“Barbie Botox”: The Systematic Review of a Popular Trend

Injectable agents have formed the cornerstone of the modern cosmetic surgery practice.1,2 Botulinum toxin type A (BTXA) inhibits the release of acetylcholine into the synaptic cleft, resulting in temporary muscle paralysis with clinical effects generally lasting 2 to 6 months.3 since its approval in 2002 for treatment of glabellar facial lines, BTXA has since expanded to include off-label treatments for a variety of other cosmetic as well as neuromuscular conditions and its injection is now the most frequently performed cosmetic procedure in the United States.

Source: Journal of Plastic, Reconstructive and Aesthetic Surgery - November 4, 2023 Category: Cosmetic Surgery Authors: Sarah E. Diaddigo, Myles N. Lavalley, Paul A. Asadourian, Christine H. Rohde Source Type: research