Alternative Splicing Factor HNRNPU as a Promising Biomarker for Gastric Cancer Risk and Prognosis with Tumor-Promoting Properties

In this study, the expression characteristics of HNRNPU were analyzed by the TCGA data, GEO data, then further identified by real-time quantitative PCR and immunohistochemistry using tissue specimens. From superficial gastritis, atrophic gastritis, hyperplasia to GC, the in situ expression of HNRNPU protein gradually increased, and the AUCs for diagnosis of GC and its precancerous lesions, GC were 0.911, 0.847, respectively.
Source: American Journal of Pathology - Category: Pathology Authors: Tags: Regular Article Source Type: research