Alternative Splicing Factor HNRNPU as a Promising Biomarker for Gastric Cancer Risk and Prognosis with Tumor-Promoting Properties
In this study, the expression characteristics of HNRNPU were analyzed by the TCGA data, GEO data, then further identified by real-time quantitative PCR and immunohistochemistry using tissue specimens. From superficial gastritis, atrophic gastritis, hyperplasia to GC, the in situ expression of HNRNPU protein gradually increased, and the AUCs for diagnosis of GC and its precancerous lesions, GC were 0.911, 0.847, respectively.
Source: American Journal of Pathology - Category: Pathology Authors: Ying-ying Dong, Meng-ya Wang, Jing-jing Jing, Yi-jun Wu, Hao Li, Yuan Yuan, Li-ping Sun Tags: Regular Article Source Type: research
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