9. Implementation survey of the ACMG/CGC standards for interpretation of acquired CNAs and CN-LOH in neoplastic disorders

These standards introduced a categorization system for the interpretation and reporting of acquired CNAs and CN-LOH in neoplastic disorders (PMID: 31138931). Three years after their publication, the workgroup developed a survey to gauge implementation of the standards in clinical laboratories. Part 1 of the survey was focused on clinical implementation data and part 2 on laboratory practices. The survey was distributed through CGC, and 32 responses from 4 continents were received. 75% of participants reported that they either fully or partially implemented the standards in their laboratories.
Source: Cancer Genetics and Cytogenetics - Category: Genetics & Stem Cells Authors: Source Type: research