87. A tale of two aspirates: sequential pulls of bone marrow yield discordant results in hepatosplenic T-cell lymphoma

We present a case of a 33-year-old female with a recent diagnosis of HSTCL from an outside institution referred to Vanderbilt University Medical Center (VUMC) in late 2022. Bone marrow (BM) biopsies from VUMC and the outside institution-performed 16 days apart-had similar immunophenotypic and morphologic findings: an abnormal T-cell lymphocyte population positive for CD3, CD56, and gamma delta, negative for CD5 and alpha beta, and an intrasinusoidal distribution.

Source: Cancer Genetics and Cytogenetics - November 1, 2023 Category: Genetics & Stem Cells Authors: Barbara Nelson, Rebecca Smith, Cindy Vnencak-Jones, Laura Lee, Aaron Shaver, Mary Ann Thompson Arildsen, Barbara Sommer, Yingda Wang, Ashwini Yenamandra Source Type: research