Associations Between Buprenorphine\Naloxone and Methadone Treatment and non-Opioid Substance Use in Prescription-Type Opioid Use Disorder: Secondary Analyses From the OPTIMA Study

CONCLUSION: Methadone did not show a significant effect on overall non-opioid substance use in POUD compared to BUP/NX treatment but was associated with lower odds of benzodiazepine and THC use in particular. Non-opioid substance use did not predict OAT outcomes. Further research is needed to ascertain whether specific patterns of polysubstance use (quantity and frequency) may affect treatment outcomes.PMID:37899716 | DOI:10.1177/07067437231210796

Source: Canadian Journal of Psychiatry - October 30, 2023 Category: Psychiatry Authors: Hamzah Bakouni Heidar Sharafi Sarah Drouin Raphaelle Fortin St éphanie Marsan Suzanne Brissette Maria Eugenia Socias Bernard Le Foll Ron Lim Didier Jutras-Aswad Source Type: research