DNA methylation of insulin signaling pathways is associated with HOMA2-IR in primary myoblasts from older adults

While ageing is associated with increased insulin resistance (IR), the molecular mechanisms underlying increased IR in the muscle, the primary organ for glucose clearance, have yet to be elucidated in older in...

Source: Skeletal Muscle - October 28, 2023 Category: Research Authors: Mark A. Burton, Emma S. Garratt, Matthew O. Hewitt, Hanan Y. Sharkh, Elie Antoun, Leo D. Westbury, Elaine M. Dennison, Nicholas C. Harvey, Cyrus Cooper, Julia L. MacIsaac, Michael S. Kobor, Harnish P. Patel, Keith M. Godfrey and Karen A. Lillycrop Tags: Research Source Type: research