Sex dimorphism and cancer immunotherapy: may pregnancy solve the puzzle?

In the last decade, growing interest has emerged about sex dimorphism of immune response in the context of anti-cancer immunotherapy. Specifically, sex includes physiological and anatomical variables such as chromosome asset and organization, reproductive organs and sex hormones levels which can ultimately affect the pathogenesis of several diseases, including cancer [1].

Source: Cancer Treatment Reviews - October 27, 2023 Category: Cancer & Oncology Authors: Francesco Maria Venanzi, Marta Bini, Antonio Nuccio, Alessandro De Toma, Matteo Lambertini, Francesca Rita Ogliari, Sara Oresti, Maria Grazia Vigan ò, Elena Brioschi, Maggie Polignano, Matteo Maria Naldini, Silvia Riva, Michele Ferrara, Nicola Fogale, Gi Tags: Anti-tumour Treatment Source Type: research