Effect of residual platelets in frozen-thawed plasma on results of dilute Russell's viper venom time assay for lupus anticoagulant testing

CONCLUSIONS: Residual platelets in plasma samples result in shortening of DRVVT assay after 1 freeze-thaw cycle. This may result in a false-negative LAC test result.PMID:37878771 | DOI:10.1093/ajcp/aqad138

Source: American Journal of Clinical Pathology - October 25, 2023 Category: Pathology Authors: Brenda J Nelson Strande Meera Sridharan Rachel R Leger Melissa S Stuart Julie I Tange Serena D Navitska Nahla Heikal Aneel A Ashrani Dong Chen Jansen N Seheult Rajiv K Pruthi Source Type: research