Molecules, Vol. 28, Pages 7294: A New and Rapid HPLC Method to Determine the Degree of Deacetylation of Glutaraldehyde-Cross-Linked Chitosan

In this study, we prepare three calibration curves (with an R2 value over 0.92) for three series of reticulated polymers covering a large range of reticulation levels to demonstrate that a correlation can be established between the LR established via HPLC and the DDA obtained via titration. The polymers are derived from three different chitosan starting materials. These standard calibration curves are now used on a routine basis in our lab, and the HPLC method has allowed us to change our DDA analysis time from 20 h to 5 min.

Source: Molecules - October 27, 2023 Category: Chemistry Authors: Ons Amamou Jean-Philippe Denis Élise Heinen Taoufik Boubaker S ébastien Cardinal Tags: Article Source Type: research