HIV-1-specific T-cell responses and exhaustion profiles in people with HIV after switching to dual therapy vs. maintaining triple therapy based on integrase inhibitors

CONCLUSIONS: Our results suggest that simplification to DT does not negatively influence the HIV-1-specific T-cell response or the exhaustion phenotype after 96 weeks of follow-up.PMID:37871555 | DOI:10.1016/j.biopha.2023.115750

Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - October 23, 2023 Category: Drugs & Pharmacology Authors: Esperanza Mu ñoz-Muela Mar ía Trujillo-Rodríguez Ana Serna-Gallego Abraham Saborido-Alconchel Ezequiel Ruiz-Mateos Luis F L ópez-Cortés Alicia Guti érrez-Valencia Source Type: research