Still running fast: Plasmodium ookinetes and sporozoites 125 years after their discovery

Trends Parasitol. 2023 Oct 19:S1471-4922(23)00236-2. doi: 10.1016/j.pt.2023.09.015. Online ahead of print.ABSTRACTPlasmodium ookinetes and sporozoites were discovered 125 years ago by MacCallum (J. Exp. Med. 1898;3:117-136) and Ross (Ind. Med. Gaz. 1899;34:1-3), respectively. While the migration capacity of ookinetes was noted immediately, the movements of sporozoites remained enigmatic for decades. Today, we know many proteins involved in parasite migration and start to conceptualize a mechanistic understanding of motility.PMID:37865610 | DOI:10.1016/j.pt.2023.09.015

Source: Trends in Parasitology - October 21, 2023 Category: Parasitology Authors: Mirko Singer Friedrich Frischknecht Source Type: research