Synthetic Methods for Various Chromeno-fused Heterocycles and their Potential as Antimicrobial Agents

Med Chem. 2023 Oct 6. doi: 10.2174/0115734064274748231005074100. Online ahead of print.ABSTRACTChromenes are a significant family of heterocyclic chemicals that have a wide range of biological applications, a simple chemical structure, and only mildly undesirable side effects. The synthesis of a wide range of chromene analogs that displayed unexpected behaviors via numerous mechanisms was investigated by a number of different research teams, which led to the discovery of multiple pathways for their synthesis. In addition, different chromene-fused heterocycles exhibit a wide variety of fascinating biological actions, including those that are anticancer, anticonvulsant, antibacterial, anticholinesterase, antituberculosis, and anti-diabetic. In light of this, the purpose of this study is to highlight the many synthesis techniques and antibacterial activity associated with chromene-fused heterocyclic compounds. Moreover, such research can open avenues for exploring other therapeutic applications of these compounds in various disease areas, as their biological activities extend beyond antibacterial effects.PMID:37855281 | DOI:10.2174/0115734064274748231005074100
Source: Medicinal Chemistry - Category: Chemistry Authors: Source Type: research