Identification of dual STRN-NTRK2 rearrangements in a high grade sarcoma, with good clinical response to first-line larotrectinib therapy

Among the three NTRK genes, NTRK2 possesses a tremendous structural complexity and involves tumorigenesis of several types of tumors. To date, only STRN and RBPMS are identified in the fusion with NTRK2 in adult ...

Source: Diagnostic Pathology - October 21, 2023 Category: Pathology Authors: Ruihe Lin, Atrayee Basu Mallick, Zi-Xuan Wang, Scot Andrew Brown, Bo Lu and Wei Jiang Tags: Case Report Source Type: research