Distinguishing the effects of systemic CSF1R inhibition by PLX3397 on microglia and peripheral immune cells

Microglia, the primary immune cells of the central nervous system (CNS), are derived from the yolk sac and populate the brain during development. Once microglia migrate to the CNS, they are self-renewing and r...

Source: Journal of Neuroinflammation - October 21, 2023 Category: Neurology Authors: Akhabue K. Okojie, Joseph O. Uweru, Morgan A. Coburn, Sihan Li, Vivian D. Cao-Dao and Ukpong B. Eyo Tags: Research Source Type: research