Genetic screening for anticancer genes highlights FBLN5 as a synthetic lethal partner of MYC

When ectopically overexpressed, anticancer genes, such as TRAIL, PAR4 and ORCTL3, specifically destroy tumour cells without harming untransformed cells. Anticancer genes can not only serve as powerful tumour spec...

Source: Cell Communication and Signaling - October 20, 2023 Category: Molecular Biology Authors: Motasim Masood, Qize Ding, Adam D. Cawte, David S. Rueda, Stefan W. Grimm, Ernesto Yag üe and Mona El-Bahrawy Tags: Research Source Type: research