Phospholipase D4 as a signature of toll-like receptor 7 or 9 signaling is expressed on blastic T-bet  + B cells in systemic lupus erythematosus

In systemic lupus erythematosus (SLE), autoreactive B cells are thought to develop by-passing immune checkpoints and contribute to its pathogenesis. Toll-like receptor (TLR) 7 and 9 signaling have been implica...

Source: Arthritis Research and Therapy - October 16, 2023 Category: Rheumatology Authors: Ken Yasaka, Tomohide Yamazaki, Hiroko Sato, Tsuyoshi Shirai, Minkwon Cho, Koji Ishida, Koyu Ito, Tetsuhiro Tanaka, Kouetsu Ogasawara, Hideo Harigae, Tomonori Ishii and Hiroshi Fujii Tags: Research Source Type: research