Development and internal validation of a clinical prediction model for individualized dosing of BAY 81-8973, A full-length recombinant factor VIII, in pediatric patients with haemophilia A

As the most commonly used coagulation factor VIII (FVIII) concentrate in China, the individualized dosing prediction model of Kovaltry (BAY81 –8973) is not fully investigated in pediatric patients. The prophylaxis tailored by population pharmacokinetic (PopPK) model can optimize dosing regimens.

Source: Thrombosis Research - October 13, 2023 Category: Hematology Authors: Huan He, Kun Huang, Xiaoling Cheng, Xinyi Wu, Runhui Wu, Xiaoling Wang Tags: Full Length Article Source Type: research