Synergistic roles of CBX4 chromo and SIM domains in regulating senescence of primary human osteoarthritic chondrocytes

Cellular senescence is a critical factor contributing to osteoarthritis (OA). Overexpression of chromobox homolog 4 (CBX4) in a mouse system was demonstrated to alleviate post-traumatic osteoarthritis (PTOA) b...

Source: Arthritis Research and Therapy - October 12, 2023 Category: Rheumatology Authors: Yu-Hsiu Chen, Xin Zhang, David Attarian and Virginia Byers Kraus Tags: Research Source Type: research