Fas ligand intracellular signaling: does PSTPIP mediate T cell death?

AbstractFas and Fas ligand (FasL)-induced cell death is critical for the appropriate regulation of immune responses, especially those mediated by T cells. In this letter, several studies are discussed that reinforce the importance of FasL intracellular signaling for CD4  + T cell death, which might involve PSTPIP phosphatase and/or MAPKs.

Source: Apoptosis - October 4, 2023 Category: Molecular Biology Source Type: research