The feasibility of endoscopic resection for colorectal laterally spreading tumors

AbstractThe present study aimed to investigate the feasibility and safety of endoscopic resection for colorectal laterally spreading tumors (LSTs) in different size groups. This retrospective study included 2699 patients with LSTs who underwent endoscopic treatment at the Second Xiangya Hospital of Central South University from May 2012 to February 2022. The patient baseline and procedure outcomes were compared between the  <  5 cm group, 5–10 cm group, and ≥ 10 cm group. Meanwhile, lesions larger than 5 cm in diameter were longitudinally compared for endoscopic safety using ESD with surgical operation outcomes. There were 2105 patients in the <  5 cm group, 547 patients in the 5–10 cm group, and 47 patients in the ≥ 10 cm group.En bloc resection andR0 resection rates, the incidence of adverse events, length of stay (LOS), and medical costs significantly differed between the groups (P <  0.01). Comorbidity of diabetes or hypertension, history of antithrombotic drug use, lesion size, location, gross type, endoscopic procedures selection, and circumferential extent of the mucosal defect were independent risk factors for delayed bleeding (P <  0.05).En bloc resection,R0 resection, and lesion canceration were associated with local recurrence. For lesions larger than 5  cm in diameter, ESD had similarR0 resection and local recurrence rates compared with a surgical operation but a loweren bloc rate, LOS, and medical costs. Expert ...
Source: Updates in Surgery - Category: Surgery Source Type: research