Differential sperm histone retention in normozoospermic ejaculates of infertile men negatively affects sperm functional competence and embryo quality

Discussion and conclusionHistone retention in spermatozoa can be one of the factors behind the development of idiopathic male infertility. Such spermatozoa may influence embryonic behaviour and thereby affect the success rate of assisted reproductive technology procedures. These results, although descriptive in nature, warrant further research to address the underlying mechanisms behind these clinically important observations.

Source: Andrology - October 7, 2023 Category: Urology & Nephrology Authors: Riddhi Kirit Pandya, Ameya Jijo, Aswathi Cheredath, Shubhashree Uppangala, Sujith Raj Salian, Vani R Lakshmi, Pratap Kumar, Guruprasad Kalthur, Sanjay Gupta, Satish Kumar Adiga Tags: ORIGINAL ARTICLE Source Type: research