Chromatographic purification of small extracellular vesicles using an affinity column for phospholipid membranes

CONCLUSION: The sEVs were effectively purified in the bind-elute mode and the ExoPUA column can be refreshed and sterilized with sodium hydroxide (NaOH), having high potential for multiple sEV purification in a scalable and industrial manner.PMID:37787831 | DOI:10.1007/s10529-023-03430-7

Source: Biotechnology Letters - October 3, 2023 Category: Biotechnology Authors: Kanako Masaki Abo Bakr F Ahmed Takenori Ishida Yuuki Mikami Hisakage Funabashi Ryuichi Hirota Takeshi Ikeda Akio Kuroda Source Type: research