Effector translocation and rational design of disease resistance

Trends Microbiol. 2023 Sep 29:S0966-842X(23)00269-X. doi: 10.1016/j.tim.2023.09.007. Online ahead of print.ABSTRACTThe effector repertoire of a pathogen is dynamically evolving. However, the effector translocation mechanism, partly elucidated recently, may be conserved. By targeting the effector translocation machinery, rather than the individual evolving effector, rational design of durable and broad-spectrum disease resistance can be achieved, facilitated by genome-editing and artificial intelligence-enabling technologies.PMID:37778925 | DOI:10.1016/j.tim.2023.09.007

Source: Trends in Microbiology - October 1, 2023 Category: Microbiology Authors: Gan Sha Guotian Li Source Type: research