High glucose environment induces NEDD4 deficiency that impairs angiogenesis and diabetic wound healing
Healing of diabetic wounds, characterized by impaired angiogenesis, remains a clinical challenge. E3 ligase have been identified as potential therapeutic targets of wound healing.
Source: Journal of Dermatological Science - Category: Dermatology Authors: Yu Guo, Yongjie Wang, Haiwei Liu, Xulei Jiang, Shaorong Lei Source Type: research