Biomolecular condensates in kidney physiology and disease

Nature Reviews Nephrology, Published online: 26 September 2023; doi:10.1038/s41581-023-00767-0Biomolecular condensates are membraneless compartments that typically contain proteins and RNAs and broadly affect many cell types and organs. In the kidney in particular, rapid and reversible assembly of biomolecular condensates occurs through the process of hyperosmotic phase separation. This Review describes emerging evidence for, and the impact of, biomolecular condensates on kidney physiology and disease.
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Authors: Source Type: research