Iliac crest bone graft versus cell-based grafts to augment spinal fusion: a systematic review and meta-analysis

ConclusionCell-based therapy offers a promising alternative to ICBG in spinal fusion surgery, which could help reduce the associated morbidity to patients. This review found that cell-based therapy is non-inferior to iliac crest bone graft and may offer patients an alternative treatment option with fewer complications and reduced post-operative pain. However, the literature to date is limited by heterogeneity of the cell preparation and grafting process. Future research with a unified approach to the cell preparation process is required to fully delineate the potential advantages of this technology.
Source: European Spine Journal - Category: Orthopaedics Source Type: research