GSE213981 Endogenous B cell TACI-Short-APRIL signaling

Contributors : Miguel Fribourg ; Yolanda CarmonaSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensHere we show that TACI-S increases its expression with maturation and colocalizes in the intracellular compartment with the ligand APRIL. APRIL downregulation in human B cells, eliminated class switch. These studies suggest the importance of intracellular APRIL together with TACI-S in maintaining humoral immunity.

http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE213981

Source: GEO: Gene Expression Omnibus - September 22, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research

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