Ceruloplasmin regulating fibrosis in orbital fibroblasts provides a novel therapeutic target for Graves ’ orbitopathy

ConclusionCP was downregulated in GO and suppressed the expression of fibrosis-associated proteins in both GO and normal OFs. CP might serve as a promising therapeutic agent in the treatment regimens for GO.
Source: Journal of Endocrinological Investigation - Category: Endocrinology Source Type: research