Tumor-infiltrating normal B cells revealed by immunoglobulin repertoire clonotype analysis are highly prognostic and crucial for antitumor immune responses in DLBCL

CONCLUSIONS: TIL-B frequency is a significant prognostic factor in DLBCL and plays a crucial role in antitumor immune responses. This study provides novel insights into the prognostic determinants in DLBCL and TIL-B functions with important therapeutic implications.PMID:37728879 | DOI:10.1158/1078-0432.CCR-23-1554

Source: Clinical Cancer Research - September 20, 2023 Category: Cancer & Oncology Authors: Zijun Y Xu-Monette Yong Li Thomas Snyder Tiantian Yu Tingxun Lu Alexandar Tzankov Carlo Visco Govind Bhagat Wenbin Qian Karen Dybkaer April Chiu Wayne Tam Youli Zu Eric D Hsi Fredrick B Hagemeister Yingjun Wang Heounjeong Go Maurilio Ponzoni Andr és J M Source Type: research