The melatonin agonist ramelteon attenuates bleomycin-induced lung fibrosis by suppressing the NLRP3/TGF- Β1/HMGB1 signaling pathway

CONCLUSIONS: The severity of fibrosis decreased with ramelteon application. These effects of ramelteon may be associated with NLRP3 inflammation cascade.PMID:37716182 | DOI:10.1016/j.advms.2023.09.004

Source: Advances in Medical Sciences - September 16, 2023 Category: Biomedical Science Authors: Pelin Aydin Zeynep B Aksakalli-Magden Maide S Civelek Sevgi Karabulut-Uzuncakmak Behzad Mokhtare Mustafa Ozkaraca Fatih Alper Zekai Halici Source Type: research