Attenuated airways inflammation and remodeling in IL-37a and IL-37b transgenic mice with an ovalbumin-induced chronic asthma

CONCLUSION: Our data suggest that both IL-37a and IL-37b isoforms are able to not only ameliorate airways inflammation and airways hyperresponsiveness, but also greatly reduce airways structural changes of animal models of chronic asthma.PMID:37689011 | DOI:10.1016/j.cellimm.2023.104759

Source: Cellular Immunology - September 9, 2023 Category: Allergy & Immunology Authors: Lele Cui Xiaofeng Qin Tingting Fu Chenduo Li Dan Wang Yue Hu Yan Li Yan Chen Ye Cui Jingjing Wang Huihui Yuan Zhe Lv Jie Liu Damo Xu Rongfei Wei Sun Ying Wei Wang Source Type: research