Viruses, Vol. 15, Pages 1932: Treatment Emergent Dolutegravir Resistance Mutations in Individuals Na & iuml;ve to HIV-1 Integrase Inhibitors: A Rapid Scoping Review

Conclusions: Among INSTI-naïve PLWH with VF and treatment emergent INSTI-associated DRMs, most developed one of four signature DRMs, most commonly R263K or G118R. G118R was associated with a much greater reduction in DTG susceptibility than R263K.

Source: Viruses - September 15, 2023 Category: Virology Authors: Kaiming Tao Soo-Yon Rhee Carolyn Chu Ava Avalos Amrit K. Ahluwalia Ravindra K. Gupta Michael R. Jordan Robert W. Shafer Tags: Review Source Type: research