Autoimmune disease, including Lupus Panniculitis in association with Panniculitic Cell Lymphomas

Some T cell lymphomas exhibit unique homing properties of the neoplastic lymphocytes for the subcutaneous fat. There are two primary forms of subcutaneous panniculitic lymphomas of T cell origin. The first falls under the designation of primary cutaneous gamma delta T cell lymphomas of the fat (PGD-TCL). The neoplastic cells are double negative for CD8+ gamma delta T cells and often have an aggressive clinical course. The other form of panniculitis, T cell lymphoma, falls under the designation of subcutaneous panniculitis-like T cell lymphoma (SPTCL).

Source: Clinics in Dermatology - September 14, 2023 Category: Dermatology Authors: Cynthia M. Magro, Taylor Kalomeris, Alicia Dillard Source Type: research