Topographic Correlation of Microperimetry with Structural Characteristics in Diabetic Macular Ischemia

The global burden of diabetes-related visual impairment is increasing with the rising prevalence of diabetes.1 Diabetic macular ischemia (DMI), defined as an enlarged foveal avascular zone (FAZ) and/or parafoveal capillary nonperfusion, is a cause of vision loss in diabetic retinopathy (DR).2,3 The prevalence of DMI increases as the severity of DR worsens, with the highest prevalence (77%) reported in proliferative diabetic retinopathy (PDR).4 Currently, there are no treatment options for DMI.5-7 As novel interventions are being interrogated (NCT04424290 and NCT04919499 in clinical trials.gov), a functional endpoint that provides a precise topographic correlation to structural characteristics in DMI is required.
Source: American Journal of Ophthalmology - Category: Opthalmology Authors: Tags: Original Articles Source Type: research