The Co-Twin Control Design: Implementation and Methodological Considerations

This article introduces the CTCD and offers an overview of analysis methods for binary and continuous outcome and exposure variables. Tools for data simulation are provided, along with practical guidance and accompanying scripts for implementing the CTCD in R, SPSS, and Stata. While the CTCD offers valuable insights into causal inference, it depends on several assumptions that are important when interpreting CTCD results. By presenting a broad overview of the CTCD, this article aims to equip researchers with actionable recommendations and a comprehensive understanding of the design's strengths and limitations.PMID:37655521 | DOI:10.1017/thg.2023.35
Source: Twin Research and Human Genetics - Category: Genetics & Stem Cells Authors: Source Type: research